I am an Associate Teaching Professor in the Department of Biological Sciences and teach in the Biotechnology Program at North Carolina State University in Raleigh, NC. My research interests include molecular microbiology, metagenomics, epidemiology, history of diseases, science education, and open educational practices. I am also interested in the teaching with technology and the scholarship of teaching and learning. I want to be a reflective teacher and curious scientist with the goal of learning with and from students and staff at NC State and beyond. Let’s find a time to chat!
Websites with Student Contributions
- The Delftia Project (citizen science and undergraduate research)
- BIT 477/577 Metagenomics Course
- BIT 479/579 High-throughput Discovery Course
- BIT 480/580 Yeast Metabolic Engineer with Dr. Claire L. Gordy
- BIT 295 Biotechnology & Sustainability (in design)
- NSF RCN HITS: Inquiry-based case studies about high-throughput discovery with Dr. Sabrina Robertson (UNC Chapel Hill)
- NIH IPERT: MBLEMs: Molecular Biotechnology Laboratory Education Modules with Dr. Bob Kelly and Biotechnology Program
- CCCOER Regional Leaders of Open Education with Dr. Karen Cangialosi (Keene)
- ccgoller.com personal website and blog
- BioQUEST/QUBES and CourseSource!
Hablo español y me encanta platicar sobre microbiología, ciencias, y diferentes carreras. Mi objectivo es aprender con ustedes y fomentar la curiosidad y el respeto mutuo. Juntos podemos crear y descubrir. Encontremos momento para platicar.
B.S. Biology and Biotechnology Worcester Polytechnic Institute 2008
Ph.D. Microbiology and Molecular Genetics Emory University 2008
The Hartwell Foundation Postdoctoral Fellowship Anti-infectives and Microbial Pathogenesis Duke University Medical Center 2009-2012
Postdoctoral Teaching Scholar Molecular Biology Education / Metagenomics North Carolina State University 2012-2015
Area(s) of Expertise
Molecular Biology Education
High-throughput Discovery and Lab Automation
- Divide and Conquer: A Simple Modern Technique for Collaborative Small Group Learning with Reciprocal Peer Teaching , Journal of Microbiology and Biology Education (2021)
- HITS: A network to create inquiry-based case studies that make high-throughput approaches and discovery accessible , (2021)
- Integrating Bioinformatics Tools Into Inquiry-Based Molecular Biology Laboratory Education Modules , FRONTIERS IN EDUCATION (2021)
- New Tricks for Old Drugs: Using High-throughput Screening to Repurpose FDA-Approved Drugs to Combat Zika Virus , National Center for Case Study Teaching in Science (2021)
- Sharing Notes is Encouraged: Annotating and Co-creating with Hypothes.is and Google Docs , Journal of Microbiology & Biology Education (2021)
- Single Cell Insights Into Cancer Transcriptomes: A Five-Part Single-Cell RNAseq Case Study Lesson , CourseSource (2021)
- Three steps to adapt case studies for synchronous and asynchronous online learning , Journal of Microbiology and Biology Education (2021)
- A CRISPR/Cas guide RNA design in silico activity , CourseSource (2020)
- Aerobic biodegradation in freshwater and marine environments of textile microfibers generated in clothes laundering: Effects of cellulose and polyester-based microfibers on the microbiome , Marine Pollution Bulletin (2020)
- COVID-19: Where Did You Come From, Where Did You Go? National Center for Case Study Teaching in Science , National Center for Case Study Teaching in Science (2020)
Overview. For modern life science researchers, high-throughput approaches can open the doors to discovery of novel genes, drugs, and regulatory networks. The effective design, implementation, and analysis of high-throughput research requires fundamental quantitative skills. Taken together, the opportunity for new modes of discovery and development of associated quantitative skills makes integration of high-throughput research into college biology curricula highly attractive. Yet, the high cost and technological demands of high-throughput discovery prohibit its use in most college laboratories. To address this need, the proposed Research Coordination Network in Undergraduate Biology Education (RCN-UBE) seeks to improve student quantitative skills and participation in high-throughput discovery. Researchers and teaching fellows in the network will learn about high-throughput technologies and work together to create novel case studies that will demystify high-throughput approaches and promote discovery science to reinforce cornerstone STEM concepts and quantitative skills in the college classroom. The specific objectives of this network are to: â— Provide workshops, a virtual community, and online resources to foster high-throughput research and its integration into the classroom â— Connect researchers and educators to design and assess quantitative biology case studies based on high-throughput discovery research â— Create a diverse consortium of institutions committed to implementing these quantitative educational tools in biology courses and curricula across the country and world Steering Committee: 1. Dr. Carlos Goller, NCSU Biotechnology Program, Raleigh, NC. [PI; molecular biology education] 2. Dr. Sabrina Robertson, NCSU Biotechnology Program, Raleigh, NC. [Co-PI; molecular biology education] 3. Dr. Sam Donovan, University of Pittsburgh, PA. [QUBES and virtual mentoring] 4. Dr. Patricia Marsteller, Emory University, Atlanta, GA. [Case study design] 5. Dr. Mark Melton, Saint Augustineâ€™s University, Raleigh, NC. [Assessment & evaluation] 6. Dr. Mark Pauley, University of Nebraska, Omaha, NE. [Bioinformatics competencies] 7. Dr. Conner Sandefur UNCP, Pembroke, NC. [Undergraduate partner institutions] 8. Dr. Adriana San Miguel, NCSU, Raleigh, NC. [HT data acquisition expertise] Intellectual Merit. A research and educational network that includes primarily undergraduate institutions, early career teaching faculty, and national and international researchers will create impactful educational materials to demonstrate the transformative power of high-throughput approaches and teach underlying quantitative skills. The resulting inquiry-based case studies will engage students in authentic research and better train future scientists for jobs in modern molecular biology. Undergraduates will analyze novel data sets and develop their quantitative skills, while network participants will enhance their research and teaching through provided high-throughput technical workshops and the development of case studies with teams of network-trained faculty and postdoctoral â€œCase Fellowsâ€. Broader Impacts. This project provides training opportunities for a diverse group of undergraduates, graduate students, researchers, and educators. Educators from diverse institutions and researchers from underrepresented groups will interact at meetings. The networkâ€™s educational resources can be implemented in a variety of undergraduate curricula and will be widely disseminated through publications, presentations, workshops, and web access to encourage adoption, adaptation, assessment, and creation of cases that use high-throughput approaches and data.
The goal of this event is to create the infrastructure for an inclusive research experience that is open to all students. To achieve this goal, we aim to: 1. Provide mentored research experiences to students who are excluded from most traditional undergraduate research programs. 2. Engage teams of students and faculty in authentic research and open science practices. 3. Create an open research community that connects teams of students and faculty from multiple institutions and facilitates ongoing collaboration and research opportunities for students. 4. Promote a system of mentoring, collaborative data analysis (using accessible web-based tools such as KBase [DOE], Nephele [NIH], and CyVerse [NSF]), and learning that is scalable to other institutions and open for further collaboration.
Despite the accelerating expansion of online resources for modern life science education and training, the reality is that development of molecular biology laboratory-based skills requires â€˜hands-onâ€™ instruction, preferably in a research-oriented context. Keeping pace with recent scientific breakthroughs and incorporating such developments into the educational setting is challenging from both workforce and economic perspectives. Yet, educational strategies that rely on traditional, lecture alone or outdated, laboratory experiences ineffectively prepare the current and future generations of the US biomedical workforce. Here, we propose to develop and implement a new paradigm for teaching modular molecular biology-oriented laboratory courses that relate established critical skills to cutting-edge technologies in support of the professional viability of modern biologists and biotechnologists. Our overarching goal is to initiate and support a collaborative effort to â€˜teach the teachersâ€™ how to Designate, Design, Develop, Deploy and Disseminate (5-D) Molecular Biotechnology Laboratory Education Modules (MBLEMs) on cutting-edge topics across the higher education landscape. This aim will be accomplished by fostering multi-institution cooperation, creative new pedagogical approaches, and integration of interdisciplinary research and bioethics into novel educational modules. We will collaborate initially with teams of participants from five different institutions, and then add three new partners along the way, that collectively represent a broad range of higher educational missions. In support of the MBLEM effort, we will establish a virtual support network, i.e., ongoing inter-institution communication throughout the year to enable MBLEM implementation, led by faculty and teaching postdoctoral fellows at North Carolina State University (NC State). The year-long, 5-D support process will be centered around an annual summer workshop at NC State attended by representatives of our partner institutions that will nucleate interdisciplinary teams of faculty, teaching assistants (graduate students and postdoctoral fellows) and experienced MBLEM instructors. As part of this process, we will organize career development and outreach opportunities that bring together faculty and students from the partner institutions, including those that focus on serving minority students and students with disabilities, to form a supportive and inclusive community fostering modern life science laboratory training. We will also assess MBLEM dissemination and the impact of training on participating MBLEM institutions educational programs and students. Assessment will enable the identification of challenges faced at different institutions and reveal how to better train diverse groups of students in critical skills needed to be productive members of the US biomedical workforce.
The keystone of our proposed Biotechnology (BIT) Sequencing-based Undergraduate Research Experience (SURE) is student immersion in research that uses next generation sequencing (NGS) technologies to answer important biological questions. Research mentors will engage students in projects across a variety of fields including microbiology, virology, neuroscience, plant biology,epigenetics, forensics, and toxicology. The goals of our program are to 1) train students to use transformative NGS tools to propel interdisciplinary research; 2) recruit, inspire, and prepare a diverse group of students for biotechnology-related research careers; and, 3) engage participants in sharing their research and newly acquired knowledge with the academic community and, through educational outreach, with K-12 deaf and hard of hearing students. NCSUâ€™s Biotechnology Program (BIT), an interdisciplinary effort through which researchers, educators and students from over 35 departments drive innovation in biotechnology education and research, will sponsor the proposed REU. We offer research-based courses that are designed using the best evidence-based teaching practices to equip students with cutting-edge molecular biology skills. The BIT programâ€™s research education experience and infrastructure make it an ideal central training facility for young undergraduate researchers. Ten trainees will begin their 10-week experience in BIT with a NGS technology short course. In the course, students will receive laboratory safety training, learn about NGS technology through case studies, prepare samples for sequencing, and analyze data using common bioinformatic tools and NGS software. Participants will also attend weekly seminars on NGS research, biotech careers, graduate school, responsible conduct of research, and visit biotech companies in Research Triangle Park. Throughout the summer BIT SURE trainees will also work together to develop a deaf accessible K-12 outreach activity. The collaborative outreach project, social events across the Research Triangle, and activities with other local N.C. REUs will foster collegiality and long-term peer relationships amongst trainees. For the summer capstone, students will present a poster at NCSUâ€™s research symposium and an outreach activity to students from the North Carolina School for the Deaf (NCSD). Recruitment for BIT SURE will focus on underrepresented groups in STEM, including deaf and hard of hearing students, first generation college students, women, minorities and students with no prior research experience. The common web-based assessment tool used by REU programs and funded by the Division of Biological Infrastructure will be used to evaluate the training program. Students will be tracked by the BIT Program and be required to respond to an email sent via the NSF reporting system.
The National Science Foundation (NSF)-funded Research Coordination Network (RCN) for undergraduate biology education HITS: High-throughput Discovery Science & Inquiry-based Case Studies for Todayâ€™s Students hosts an annual summer workshop focusing on the use of high-throughput (HT) biotechnology approaches for scientific discovery. On the first day of the three-day workshop, participants learn about cutting-edge HT approaches with talks from distinguished speakers from the RTP area and guests. Graduate students and postdoctoral fellows selected to be HITS â€œHT Research Fellowsâ€ present on their research using HT approaches. On the second and third days, participants form interdisciplinary groups composed of researchers and educators. Facilitators and Case Fellows from the first cohort (ten faculty selected from NC colleges and universities in 2018) introduce the use of educational case studies and problem-based learning to participants. Case Fellows present examples of cases on HT topics, and groups are tasked with designing novel cases using authentic data (often unpublished and shared by labs and institutes such as Dr. Rob Dunnâ€™s group and the Allen Institute). This workshop will teach participants about novel high-throughput approaches and how they can be incorporated into college classrooms through case studies. The case studies designed as part of the HITS workshop will expose students in numerous colleges both in North Carolina and beyond to high-throughput discovery. We seek funding from the North Carolina Biotechnology Center (NCBC) to support the workshop by hosting guest speakers.
Honors and Awards
- Appointed to the National Institute on Scientific Teaching Faculty Learning Community (FALCoN) planning committee
- NSF RCN-UBE Ethics Network for Course-based Opportunities in Undergraduate Research (ENCOUR) Fellowship 2021
- Selected as Guest Editor for the Journal of Microbiology and Biology Education 2021 Themed Issue
- 2021 NC State Student Government Association Faculty Open Resource Award (inaugural)
- 2020 NC State DELTA Teaching Online Certificate Fellow
- 2020 NC State Libraries Faculty Fellow
- Appointed to the BioQUEST Board of Directors (2021)
- Promoted to Curriculum Editor for the Journal of Microbiology and Biology Education (2020)
- 2019 NSF PALM Active Learning Fellow
- OpenEd 2021: Promoting a Culture of Co-Creation and Equity through Course WordPress Sites on Advanced Molecular Technologies
- RLOE @ OE Global Connect 2021. Karen Cangialosi (OE Global|CCCOER), Rebecca Vasquez Ortiz (Santa Ana College), Carlos Goller (North Carolina State University)
- JMBE Webinar: Overview of the 2022 Themed Issue Call for Papers
- DELTA Grants Recipients for 2021-2022 Announced
- BioTA Episode 019: Virus, Vaccines, and Variants – August 2021. Host: Phil Gibson, Ph.D.
- Carlos C. Goller, Some Like It Hot! Living in Extreme Environments, ¡Algunos Prefieren lo Caliente! La Vida en Medio Ambiente Extremo, Sciences / Biotechnology Program
- Using Open Education to Precipitate Gold Nuggets of Wisdom: An Open Pedagogy Model for Crowdsourcing Notes and Citizen Science Research Using Web-Annotation. Open Education Southern Symposium (OESS). July 12, 2021. [recorded session]
- ALT 2021 Conference. Combining open pedagogy and citizen science to empower learners and educators. Panel presentation with Will Cross, Erin McKenney, and David Tully. April 21, 2021.
- Lecture Breakers Episode 82: The Reflective Professor: How One Professor Stays Curious, Keeps Learning, and Improves His Teaching with Dr. Carlos Goller – March 2021. Host: Barbi Honeycutt, Ph.D.
- Liquid Margins Episode 020 | Making Sense of Science With Social Annotation. Panel with Drs. Erin McKenney, Melissa McCartney, and Remi Kalir. March 15, 2021.
- Outside/In: 10 x 10 City Gutter – March 2021. Host: Taylor Quimby, NH Public Radio.
- How to Create a Unique Lab Project for an Online Biotechnology Course – January 2021. Written by Supriya Kamath.
- SACNAS @ NC State University. Meeting Dr. Goller. January 5, 2021.
- Opentrons Blog: User Interview with Carlos Goller from NC State University – October 2020. Written by Laurie Vezquez.