Bio

The goals of the Cowley Lab are to understand how the developmental environment impacts the epigenetic regulation of the genome, and to understand the functional consequences of this for development and disease.

Awards

2021, Second Place in the Paper of the Year Award, Society of Toxicology Molecular and Systems Biology Specialty Section
2020, Center for Human Health and the Environment Outstanding Member Award
2019, Environmental Health Sciences Core Centers Annual Meeting Early Stage Investigator Invited Poster Award
2017, National Institute of Environmental Health Sciences Career Development Award – Transition to Independent Environmental Health Scientist
2015, Ralph E. Powe Junior Faculty Enhancement Award
2012, King’s College London/The London Law Trust Medal Fellowship

Publications

• Cadmium exposure during adolescence and young adulthood induces signatures of metabolic dysfunction-associated steatotic liver disease , Scientific Reports (2025)
• Dietary Iron Supplementation Protects Against Growth Restriction and Metabolic Dysfunction‐Associated Steatotic Liver Disease in Perinatal Cadmium‐Exposed Mice , FASEB BioAdvances (2025)
• Environmental Contaminants, Iron Deficiency, and Iron‐Deficiency Anemia: A Review of the Literature , Scientifica (2025)
• The effects of developmental cadmium exposure on health and disease , Disease Models & Mechanisms (2025)
• Grb7, Grb10 and Grb14, encoding the growth factor receptor-bound 7 family of signalling adaptor proteins have overlapping functions in the regulation of fetal growth and post-natal glucose metabolism , BMC Biology (2024)
• LncRNA Tuna is activated in cadmium-induced placental insufficiency and drives the NRF2-mediated oxidative stress response , Frontiers in Cell and Developmental Biology (2023)
• Epigenetic control of the imprinted growth regulator Cdkn1c in cadmium-induced placental dysfunction , Epigenetics (2022)
• Genomic map of candidate human imprint control regions: the imprintome , Epigenetics (2022)
• The imprinted geneZac1regulates steatosis in developmental cadmium-induced nonalcoholic fatty liver disease , Toxicological Sciences (2022)
• Zac1 and the Imprinted Gene Network program juvenile NAFLD in response to maternal metabolic syndrome , Hepatology (2022)